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. 2023 Oct 7;30:84. doi: 10.1186/s12929-023-00977-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Development status and global sales forecast for mRNA-based drugs. A Composite development status of 316 mRNA-based medicines (excluding technologies that were discontinued, suspended or not updated for an extended period); analyzed with Clarivate’s Cortellis Competitive Intelligence Database on July 28, 2023. B–D Global sales forecasts to 2029 are based on analyst consensus, acquired from GlobalData’s Intelligence Center Database on June 26, 2023. B Five FDA-approved ASO (anti-sense oligo) drugs. C Five FDA-approved siRNA drugs. D Two FDA-approved mRNA vaccines are available on the market. Summary information regarding these drugs is provided in "Regulatory agency-approved drugs". Regulatory agency-approved drugs. E–G Total global sales forecasts (US$ million) for each drug up to 2029