Table 2.
Mean values ± SEM of serum insulin, oxidative stress parameters and relative expression levels of corresponding transcriptional factors in control and treated groups. Mean values within a column, not bearing a common superscript differ significantly (P ≤ 0.05).
| Group | Insulin | Total oxidant status | Total antioxidant capacity | MAFA | NKX6.1 | NEUROD | NGN-3 | PDX-1 | INS-1 | INS-2 |
|---|---|---|---|---|---|---|---|---|---|---|
| Normal control | 1.21 ± 0.0872a |
25.58 ± 1.993b | 1.64 ±0.073a |
3.23 ±0.071a |
3.34 ±0.072 a |
3.45 ±0.054 a |
2.77 ±0.19a |
2.56 ±0.09a |
2.33 ±0.071 a |
1.99 ±0.082 a |
| Negative control | 0.31 ± 0.0600c |
43.98 ±4.249a |
1.21 ±0.050d |
1.15 ±0.053d |
1.32 ±0.054 d |
1.78 ±0.083 d |
1.67 ±0.22c |
1.42 ±0.24c |
1.02 ±0.090 c |
0.94 ±0.072 d |
| Positive control | 0.78 ± 0.0600b |
33.23 ±2.333ab |
1.49 ±0.046c |
1.89 ±0.055b |
1.98 ±0.057 b |
2.47 ±0.088 b |
2.28 ±0.14b |
2.19 ±0.12b |
1.95 ±0.052 b |
1.59 ±0.082 b |
| Treatment | 1.03 ± 0.0494a |
29.67 ±6.533 b |
1.54 ±0.038b |
1.45 ±0.043c |
1.74 ±0.073 c |
2.15 ±0.082 c |
2.09 ±0.27b |
1.90 ±0.11b |
1.73 ±0.060 b |
1.24 ±0.056 c |