Table-4.
Antimicrobial resistance patterns of ESBL-producing isolates of Enterobacteriaceae among hospitalized patients at Debre Tabor Comprehensives specialized Hospital, Northwest Ethiopia.
| Isolates (n = 102) | P | Antimicrobial disks tested against the ESBL-producing isolates of Enterobacteriaceae (n = 102) |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CTR n (%) | CTX n (%) | CAZ n (%) | FOX n (%) | AMX n (%) | AMP n (%) | CIP n (%) | CHL n (%) | AZT n (%) | GM n (%) | TET n (%) | SXT n (%) | CPM n (%) | MEM n (%) | ||
| E. coli (n = 58) | S | 12 (20.7) | 9 (15.5) | 8 (13.8) | 38 (65.5) | 12 (20.7) | 50 (86.2) | 5 (8.6) | 0 | 19 (32.8) | 6 (10.3) | 0 | 0 | 53 (91.4) | 54 (93.1) |
| R | 46 (79.3) | 49 (84.5) | 50 (86.2) | 20 (34.5) | 46 (79.3) | 8 (13.8) | 53 (91.4) | 58 (100) | 39 (67.2) | 52 (89.7) | 58 (100) | 58 (100) | 5 (8.6) | 4 (6.9) | |
| K. pneumoniae (n = 34) | S | 0 | 21 (61.8) | 3 (8.8) | 27 (79.4) | 10 (29.4) | 19 (55.9) | 0 | 0 | 34 (100) | 4 (11.8) | 3 (8.8) | 0 | 21 (61.8) | 34 (100) |
| R | 34 (100) | 13 (38.2) | 31 (91.2) | 7 (20.6) | 24 (70.6) | 15 (44.1) | 34 (100) | 34 (100) | 0 | 30 (88.2) | 31 (91.2) | 34 (100) | 13 (38.2) | 0 | |
| C. freundii (n = 1) | S | 1 (100) | 1 (100) | 1 (100) | 1 (100) | 0 | 1 (100) | 0 | 0 | 1 (100) | 1 (100) | 0 | 0 | 1 (100) | 1 (100) |
| R | 0 | 0 | 0 | 0 | 1 (100) | 0 | 1 (100) | 1 (100) | 0 | 0 | 1 (100) | 1 (100) | 0 | 0 | |
| E. cloacae (n = 3) | S | 3 (100) | 2 (66.7) | 0 | 2 (66.7) | 2 (66.7) | 2 (66.7) | 1 (33.3) | 0 | 3 (100) | 0 | 1 (33.3) | 0 | 2 (66.7) | 3 (100) |
| R | 0 | 1 (33.3) | 3 (100) | 1 (33.3) | 1 (33.3) | 1 (33.3) | 2 (66.7) | 3 (100) | 0 | 3 (100) | 2 (66.7) | 3 (100) | 1 (33.3) | 0 | |
| K. oxytoca (n = 6) | S | 3 (50) | 1 (16.7) | 2 (33.3) | 6 (100) | 0 | 4 (66.7) | 0 | 1 (16.7) | 0 | 0 | 1 (16.7) | 1 (16.7) | 3 (50) | 4 (66.7) |
| R | 3 (50) | 5 (83.3) | 4 (66.7) | 0 | 6 (100) | 2 (33.3) | 6 (100) | 5 (83.3) | 2 (33.3) | 6 (100) | 5 (83.3) | 5 (83.3) | 3 (50) | 2 (33.3) | |
| Total n (%) | S | 19 (18.6) | 34 (33.3) | 14 (13.7) | 74 (72.5) | 24 (23.5) | 76 (74.5) | 6 (5.9) | 1 (1) | 57 (55.9) | 86 (84.3) | 5 (4.9) | 1 (1) | 80 (78.4) | 96 (94.1) |
| R | 83 (81.4) | 68 (66.7) | 88 (86.3) | 28 (27.5) | 78 (76.5) | 26 (25.5) | 96 (94.1) | 101 (99) | 45 (44.1) | 16 (15.7) | 97 (95.1) | 101 (99) | 22 (21.6) | 6 (5.9) | |
P-pattern, S-Sensitive, R- Resistance, Ceftriaxone (CTR), Cefotaxime (CTX), Ceftazidime (CAZ), Cefoxitin (FOX), Amoxicillin/Clavulanic acid (AMX), Ampicillin (AMP), Ciprofloxacin (CIP), Chloramphenicol (CHL), Aztreonam (AZT), Gentamicin (GM)), Tetracycline (TET), Trimethoprim-Sulfamethoxazole (STX), Cefepime (CPM), and Meropenem (MEM).