Table-5.
Antimicrobial Resistance patterns of carbapenemase-producing isolates of Enterobacteriaceae among hospitalized patients at Debre Tabor Comprehensives specialized Hospital, Northwest Ethiopia.
Isolates (n = 52) | P | Antimicrobial disks tested against the carbapenemase-producing isolates of Enterobacteriaceae (n = 52) |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CTR n (%) | CTX n (%) | CAZ n (%) | FOX n (%) | AMX n (%) | AMP n (%) | CIP n (%) | CHL n (%) | AZT n (%) | GM n (%) | TET n (%) | SXT n (%) | CPM n (%) | MEM n (%) | ||
E. coli (n = 31) | S | 10 (32.3) | 4 (12.9) | 0 | 21 (76.7) | 8 (25.8) | 3 (9.7) | 0 | 0 | 16 (51.6) | 0 | 0 | 0 | 3 (9.7) | 23 (74.2) |
R | 21 (76.7) | 27 (87.1) | 31 (100) | 10 (32.3) | 23 (74.2) | 28 (90.3) | 31 (100) | 31 (100) | 15 (48.4) | 31 (100) | 31 (100) | 31 (100) | 28 (90.3) | 8 (25.8) | |
K. pneumoniae (n = 16) | S | 7 (43.8) | 10 (62.5) | 0 | 12 (75) | 2 (12.5) | 2 (12.5) | 1 (6.3) | 0 | 14 (87.5) | 0 | 0 | 1 (6.3) | 15 (93.8) | 10 (62.5) |
R | 9 (56.2) | 6 (37.5) | 16 (100) | 4 (25) | 14 (87.5) | 14 (87.5) | 15 (93.8) | 16 (100) | 2 (12.5) | 16 (100) | 16 (100) | 15 (93.8) | 1 (6.3) | 6 (37.5) | |
C. freundii (n = 2) | S | 2 (100) | 2 (100) | 2 (100) | 2 (100) | 1 (50) | 1 (50) | 0 | 0 | 2 (100) | 1 (50) | 0 | 0 | 2 (100) | 2 (100) |
R | 0 | 0 | 0 | 0 | 1 (50) | 1 (50) | 2 (100) | 2 (100) | 0 | 1 (50) | 2 (100) | 2 (100) | 0 | 0 | |
E. cloacae (n = 1) | S | 1 (100) | 0 | 0 | 0 | 0 | 0 | 1 (100) | 0 | 1 (100) | 1 (100) | 0 | 0 | 1 (100) | 1 (100) |
R | 0 | 1 (100) | 0 | 1 (100) | 1 (100) | 1 (100) | 0 | 1 (100) | 0 | 0 | 1 (100) | 1 (100) | 0 | 0 | |
K. oxytoca (n = 2) | S | 1 (50) | 1 (50) | 1 (100) | 0 | 1 (50) | 1 (50) | 0 | 0 | 0 | 0 | 0 | 0 | 1 (50) | 1 (50) |
R | 1 (50) | 1 (50) | 0 | 2 (100) | 1 (50) | 1 (50) | 2 (100) | 2 (100) | 2 (100) | 2 (100) | 2 (100) | 2 (100) | 1 (50) | 1 (50) | |
Total n (%) | S | 21 (40.4) | 17 (32.7) | 3 (5.8) | 35 (67.3) | 12 (23.1) | 7 (13.5) | 2 (3.8) | 0 | 33 (63.5) | 2 (3.8) | 0 | 1 (2) | 22 (42.3) | 37 (71.2) |
R | 31 (59.6) | 35 (67.3) | 49 (94.2) | 17 (32.7) | 40 (76.9) | 45 (86.5) | 50 (96.2) | 52 (100) | 19 (36.5) | 50 (96.2) | 52 (100) | 51 (98) | 30 (57.7) | 15 (28.8) |