Table 3.
BBD and ANN performance statistics, prediction, and actual lipase biosynthesis by Aspergillus flavipes.
| Model | R2 | RMSE | MAD | Frequency | |
|---|---|---|---|---|---|
| Training | BBD | 0.9895 | 4.325 | 3.939 | 10 |
| ANN | 0.9955 | 2.451 | 1.531 | 10 | |
| Validation | BBD | 0.9943 | 3.269 | 2.425 | 5 |
| ANN | 0.9902 | 4.300 | 3.107 | 5 | |
| Overall |
BBD | 0.9895 | 4.004 | 3.434 | 15 |
| ANN |
0.9933 |
3.189 |
2.057 |
15 |
|
| Predicted optimum conditions | |||||
| Factor | Predicted value | ||||
| BBD | ANN | ||||
| Cultural humidity (ml water/g) | 5.8 | 5.4 | |||
| Surfactant; Brij 35 (μl/g) | 54.2 | 46.6 | |||
| Inoculum density (spore/g) | 62156610 | 100000000 | |||
| Validation of response | |||||
| Predicted lipase (U) | 214.95 | 217.72 | |||
| Experimental lipase (U) | 209.13 ± 3.27 | 218 ± 2.01 | |||
| Desirability function | 0.9470 | 0.9662 | |||
RMSE is the root squared error of the mean. MAD is the absolute deviation of the mean.