Table 3.
Summary table providing the proportions expressed in % of asymptomatic infections among dengue infections classified by the definition of ‘asymptomatic’ and the diagnostic test (the detailed tables are provided in supplementary material).
| Recruitment category | Asymptomatic definition | Virus detection | Antibody detection | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Number of studies | References | A/Id | Proportion of ‘asymptomatic’ infections (CI) | Number of studies | References | A/Id | Proportion of ‘asymptomatic’ infections (CI) | ||
| Cluster | No symptoms | 5a | [14,29,31,41,42] | 59/702 | 8% (5–12%) | 2a | [31,41] | 25/131 | 19% (10–28%) |
| Subclinical | 2a | [44,45] | 31/118 | 26% (17–35%) | 5a | [17,43,44,46,47] | 433/650 | 67% (63–71%) | |
| Unapparent | |||||||||
| Cohort | No symptoms | ||||||||
| Subclinical | 5 | [15,35,[48], [49], [50]] | 2908/3326 | 87% (86–89%) | |||||
| Unapparent | 9 | [68,69,71,73,74,[76], [77], [78], [79]] | 546/804b | 68% (64–71%) | |||||
| Serosurvey | No symptoms | ||||||||
| Subclinical | 1 | [60] | 185/215 | 86% (79–93%) | 10 | [[51], [52], [53], [54], [55], [56], [57], [58], [59],61] | 598/1305 | 46% (43–49%) | |
| Unapparent | 5 | [[80], [81], [82], [83], [84]] | 188/336c | 56% (50–61%) | |||||
| Travellers | No symptoms | 1 | [38] | 0/22 | 0% (0–21%) | ||||
| Subclinical | 1 | [62] | 0/7 | 0% (0–38%) | 7 | [21,26,[63], [64], [65], [66], [67]] | 26/96 | 27% (17–37%) | |
| Unapparent | |||||||||
a
Ref 39, 47 and 53 used both detection methods: virus or antibody detection, results have been splitted for the table.
b
Data extracted from 4/9 studies that provided detailed data.
c
Data extracted from 2/5 studies that provied detailed data.
d
Number of 'asymptomatic' dengue infection/total number of dengue infections, aggregated results extracted from the publications.