Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetic study of RLX-PNPs and RLX-suspension in Sprague-Dawley rats.
| Pharmacokinetic Parameters | RLX-PNPs | RLX-Suspension |
|---|---|---|
| AUC (μg*h/ml) | 2092.83 ± 53.64* | 263.81 ± 19.95 |
| Tmax (h) | 3.39 ± 0.12* | 2.68 ± 0.11 |
| Cmax (μg/ml) | 7.38 ± 0.49* | 1.02 ± 0.18 |
| t ½ (h) | 7.32 ± 0.73 | 7.15 ± 0.55 |
| Kel(h−1) | 5.49 ± 0.51 | 4.77 ± 0.42 |
Each value represents the mean ± S.D. (n = 6). *P < 0.05 compared to RLX-Suspension.
