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. 1998 Jun;42(6):1336–1339. doi: 10.1128/aac.42.6.1336

TABLE 2.

Pregnancy outcome for women exposed to fluoroquinolones during pregnancy compared to that for controls exposed to nonteratogenic antibiotics

Outcome or characteristic No. of women with the following outcome/ total no. of women:
Relative risk (95% confidence interval) P value
Quinolone group Nonteratogenic antibiotic group
Live births 173/200 188/200 0.92 (0.86–0.98) 0.02a
Spontanous abortion 18/200 10/200 1.80 (0.85–3.80) 0.17a
Therapeutic abortion 9/200 2/200 4.50 (0.98–20.57) 0.06a
Vaginal delivery 145/173 148/188 1.06 (0.96–1.18) 0.27a
Premature birth 11/173 13/188 0.92 (0.42–2.00) 0.99a
Birth weight, <2,500 g 7/173 9/188 0.85 (0.32–2.22) 0.93a
Fetal distress 22/173 27/188 0.89 (0.52–1.49) 0.76a
Delivery by cesarean section 28/173 40/188 0.83 (0.61–1.13) 0.21a
Gestational age 39.3 ± 2.0b 39.8 ± 2.0b 0.02c
Birth weight 3,452 ± 537d 3,477 ± 608d 0.92c
a

χ2 test (with Yates correction). 

b

Units are in weeks of gestation. 

c

Mann-Whitney rank sum test. 

d

Units are in grams.