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. 2023 Oct 7;6:1017. doi: 10.1038/s42003-023-05383-z

Table 1.

Summary of in vitro hydrodynamic performance of HCCV and control (Medtronic Freestyle Valve).

HCCV (n = 4) Medtronic Freestyle (n = 4) Significance P value
Effective orifice area (cm2) 2.15 (±0.06) 2.04 (±0.41) no 0.5994
Regurgitation fraction (%) 11.47 (±0.58) 4.56 (±1.28) yes 0.0001
Closing volume (ml) −7.02 (±1.75) −0.82 (±0.23) yes 0.0004
Leakage Volume (ml) −4.47 (±2.05) −3.73 (±1.07) no 0.5490
Peak systolic pressure gradient (mmHg) 23.37 (±1.11) 23.46 (±3.43) no 0.9606
Geometric orifice area (cm2) 3.13 (±0.14) 2.21 (±0.14) yes 0.0001
Duration of opening (s) 0.325 (±0.014) 0.302 (±0.018) no 0.0864
Opening rate (cm2/s) 74.15 (±13.00) 56.73 (±11.42) no 0.0908
Closing rate (cm2/s) −29.54 (±5.92) −22.99 (±2.72) no 0.0910

All data are represented as mean (±SD) with n = 4 independent samples.