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. 2023 Oct 7;7:53. doi: 10.1038/s41538-023-00228-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A Number of MDF per colon, of mucin depleted crypts (MDC) per colon and crypts per focus for MDF with a multiplicity (i.e. the number of crypts forming each focus) higher than 2 crypts/MDF. B Number of MDF per colon, of MDC per colon and crypts per focus for MDF with a multiplicity higher than 4 crypts/MDF. Data were represented using scatter plots with bar (mean ± sem, n = 11), significance was determined by ANOVA followed by a Dunnett’s mean comparison test. *p ≤ 0.05; **p ≤ 0.01.