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. 2023 Oct 7;14:6266. doi: 10.1038/s41467-023-42048-1

Table 1.

Characteristics of 88,818 study participants who obtained a positive or negative PCR test for SARS-CoV-2

Characteristics Tested negative Tested positive p value
(N = 51,336) (N = 37,482)
Sex
  Female 34,085 (66.4%) 23,002 (61.4%) ≤0.001
  Male 17,251 (33.6%) 14,480 (38.6%)
Age
  Mean (SD) 45.8 (13.7) 43.6 (13.9) ≤0.001
  Median [Min, Max] 49.0 [15.0, 65.0] 46.0 [15.0, 65.0]
Charlson Comorbidity Index
  0 45,984 (89.6%) 33,988 (90.7%) ≤0.001
  1 2854 (5.6%) 1967 (5.2%)
  2 1926 (3.8%) 1144 (3.1%)
  3 or more 572 (1.1%) 383 (1.0%)
Educational level (highest)
  Higher education (>5 years, MSc, PhD) 8938 (17.4%) 6799 (18.1%) ≤0.001
  Higher education (2–4 years, BSc) 17,237 (33.6%) 12,147 (32.4%)
  Higher education (1–2 years, vocational academy) 5999 (11.7%) 4067 (10.9%)
  Primary or elementary school (9th–10th grade) 4267 (8.3%) 2991 (8.0%)
  General secondary or vocational secondary education 5127 (10.0%) 4711 (12.6%)
  Vocational training 8490 (16.5%) 5755 (15.4%)
  Don’t know 1278 (2.5%) 1011 (2.7%)
Healthcare worker
  No 42,662 (83.1%) 32,284 (86.1%) ≤0.001
  Yes 8674 (16.9%) 5198 (13.9%)
Obesity
  No 38,696 (75.4%) 28,599 (76.3%) ≤0.001
  Unknown 4143 (8.1%) 2680 (7.2%)
  Yes 8497 (16.6%) 6203 (16.5%)
Fibromyalgia
  No 50,339 (98.1%) 36,783 (98.1%) 0.695
  Before test 474 (0.9%) 329 (0.9%)
Chronic fatigue syndrome
  No 49,782 (97.0%) 35,633 (95.1%) ≤0.001
  Before test 863 (1.7%) 482 (1.3%)
Anxiety
  No 45,847 (89.3%) 33,301 (88.8%) ≤0.001
  Before test 4431 (8.6%) 2994 (8.0%)
Depression
  No 43,759 (85.2%) 32,068 (85.6%) ≤0.001
  Before test 6466 (12.6%) 4249 (11.3%)
PTSD
  No 49,686 (96.8%) 36,297 (96.8%) 0.48
  Before test 1037 (2.0%) 720 (1.9%)
Asthma
  No 47,840 (93.2%) 34,643 (92.4%) ≤0.001
  Before test 3496 (6.8%) 2839 (7.6%)
Diabetes
  No 49,583 (96.6%) 36,255 (96.7%) 0.256
  Before test 1753 (3.4%) 1227 (3.3%)
High blood pressure
  No 45,412 (88.5%) 33,589 (89.6%) ≤0.001
  Before test 5924 (11.5%) 3893 (10.4%)
COPD or other lung disease
  No 50,565 (98.5%) 37,056 (98.9%) ≤0.001
  Before test 771 (1.5%) 426 (1.1%)
Chronic or frequent headaches or migraines
  No 49,212 (95.9%) 36,013 (96.1%) 0.107
  Before test 2124 (4.1%) 1469 (3.9%)

p Values for the association between test status and the survey participant characteristics were estimated using Student’s t test for continuous variables and Pearson’s Chi-squared test for categorical variables. No adjustment for multiple comparisons were made.

PTSD post-traumatic stress disorder, COPD chronic obstructive pulmonary disease.