表 1.
单纯TPOAb阳性孕妇与甲状腺功能正常孕妇的一般特征
Characteristics of isolated TPOAb positive and euthyroid pregnant women
| Items | Isolated TPOAb positive (n=1 654) | Euthyroid(n=14 792) | P value |
| Continuous variables were presented as median (1st quartile, 3rd quartile), and compared using Wilcoxon rank sum test. Categorical variables were presented as the frequency (percentage), and compared using the Chi-square test or Fisher exact test. TPOAb, thyroid peroxidase antibody; BMI, body mass index; TSH, thyroid stimulating hormone; FT4, free thyroxine. | |||
| Maternal age/years | 29.6 (27.2, 32.6) | 29.4 (27.1, 32.2) | 0.021 |
| Maternal education levels | 0.005 | ||
| Low (high school and below) | 232 (14.0) | 2 299 (15.5) | |
| Middle (vocational college) | 670 (40.5) | 6 378 (43.1) | |
| High (university and above) | 752 (45.5) | 6 115 (41.3) | |
| Current employment status | 0.115 | ||
| Yes | 1 479 (89.4) | 13 027 (88.1) | |
| No | 175 (10.6) | 1 765 (11.9) | |
| Parity | 0.918 | ||
| Primipara | 925 (55.9) | 8 297 (56.1) | |
| Multipara | 729 (44.1) | 6 495 (43.9) | |
| Pre-pregnancy BMI | 0.637 | ||
| Underweight | 165 (10.0) | 1 443 (9.8) | |
| Normal weight | 1 052 (63.6) | 9 599 (64.9) | |
| Overweight | 348 (21.0) | 2 928 (19.8) | |
| Obesity | 89 (5.4) | 822 (5.6) | |
| Gestational age at thyroid function testing/weeks | 9.0 (8.0, 10.1) | 9.0 (8.0, 10.3) | 0.623 |
| TSH/(mIU/L) | 1.1 (0.7, 1.6) | 0.9 (0.5, 1.3) | ＜ 0.001 |
| FT4/(pmol/L) | 13.5 (12.5, 14.7) | 13.6 (12.7, 14.8) | ＜ 0.001 |