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Activities of HMR 3004 and RU 66252 against MLSB-resistant strains used in fusion experiments
| Speciesa | MIC (μg/ml)
|
||
|---|---|---|---|
| Erythromycin | HMR 3004 | RU 66252 | |
| S. pneumoniae HM28 (MLSBi) | 128 | 0.12 | 8 |
| S. pneumoniae HM34 (MLSBi) | 1,000 | 0.12 | 16 |
| S. pneumoniae HM30 (MLSBi) | 2,000 | 2 | 8 |
| E. faecalis HM3 (MLSBi) | 1,000 | 4 | 8 |
| S. agalactiae HM1081 (MLSBc) | 2,000 | 8 | 8 |
MLSBi, inducible resistance to MLSB antibiotics; MLSBc, constitutive resistance to MLSB.
