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. 2023 Jul 30;7(19):5817–5824. doi: 10.1182/bloodadvances.2023010723

Table 4.

Data on post-SVR liver stiffness measurement (LSM) matched with the most important clinical and US features suggestive of advanced fibrosis/cirrhosis

Post-SVR LSM categories (kPa)
<10 (n = 80), n (%) 10-15 (n = 4), n (%) ≥15 (n = 6), n (%) P (linear trend)
At least 1 US sign suggestive of cirrhosis 23 (29) 4 (100) 5 (83) <0.001
Irregular or nodular liver surface 9 (11) 3 (75) 5 (83) <0.001
Liver caudate lobe hypertrophy 4 (5) 1 (25) 1 (17) 0.124
Splenomegaly 17 (22) 3 (75) 5 (83) <0.001
Portal vein dilatation 4 (5) 1 (25) 1 (17) 0.124
History of previous decompensation 1 (1) 1 (25) 2 (33) <0.001
History of esophageal varices 2 (3) 3 (75) 3 (50) 0.045
NAFLD 29 (36) 1 (25) 0 0.068
Alcohol consumption (7-14 AU per week) 9 (11) 0 1 (17) 0.889
Alcohol consumption (>14 AU per week) 10 (13) 1 (25) 1 (17) 0.613
At least 1 metabolic risk factor 58 (73) 3 (75) 6 (100) <0.001
Platelet count <1.5 × 105 /μL 6 (8) 1 (25) 3 (50) 0.223
Platelet count <1.1 × 105 /μL 1 (1) 1 (25) 2 (33) <0.001