Table 4.
Data on post-SVR liver stiffness measurement (LSM) matched with the most important clinical and US features suggestive of advanced fibrosis/cirrhosis
Post-SVR LSM categories (kPa) |
||||
---|---|---|---|---|
<10 (n = 80), n (%) | 10-15 (n = 4), n (%) | ≥15 (n = 6), n (%) | P (linear trend) | |
At least 1 US sign suggestive of cirrhosis | 23 (29) | 4 (100) | 5 (83) | <0.001 |
Irregular or nodular liver surface | 9 (11) | 3 (75) | 5 (83) | <0.001 |
Liver caudate lobe hypertrophy | 4 (5) | 1 (25) | 1 (17) | 0.124 |
Splenomegaly | 17 (22) | 3 (75) | 5 (83) | <0.001 |
Portal vein dilatation | 4 (5) | 1 (25) | 1 (17) | 0.124 |
History of previous decompensation | 1 (1) | 1 (25) | 2 (33) | <0.001 |
History of esophageal varices | 2 (3) | 3 (75) | 3 (50) | 0.045 |
NAFLD | 29 (36) | 1 (25) | 0 | 0.068 |
Alcohol consumption (7-14 AU per week) | 9 (11) | 0 | 1 (17) | 0.889 |
Alcohol consumption (>14 AU per week) | 10 (13) | 1 (25) | 1 (17) | 0.613 |
At least 1 metabolic risk factor | 58 (73) | 3 (75) | 6 (100) | <0.001 |
Platelet count <1.5 × 105 /μL | 6 (8) | 1 (25) | 3 (50) | 0.223 |
Platelet count <1.1 × 105 /μL | 1 (1) | 1 (25) | 2 (33) | <0.001 |