Fig. 2.

Construction of prognostic models based on genes selected from independent cross-link analysis of IEDs and their first-neighbor genes. (a) The vertical line indicates the minimum partial likelihood deviation of the least absolute shrinkage and selection operator (LASSO) coefficient distribution. The two vertical dashed lines are λ.min and λ.1se. (b) LASSO coefficient profiles of these candidate genes with non-zero coefficients determined by the optimal λ. (c) Risk score and survival status of patients in the Cancer Genome Atlas (TCGA) cohort determined using the five genes.