Table 1.
Baseline characteristics of the overall and propensity score-matched esophageal cancer patient cohorts
| Characteristics |
Before matching (n = 1205)
|
After matching (n = 808)
|
||||
|---|---|---|---|---|---|---|
| Patients without CVMD (n = 794) | Patients with CVMD (n = 411) | P value | Patients without CVMD (n = 404) | Patients with CVMD (n = 404) | P value | |
| Sex | 0.002 | 0.437 | ||||
| Male | 508 (64.0) | 225 (54.7) | 214 (53.0) | 225 (55.7) | ||
| Female | 286 (36.0) | 186 (45.3) | 190 (47.0) | 179 (44.3) | ||
| Age | < 0.001 | 0.471 | ||||
| ≤ 60 years | 263 (33.1) | 80 (19.5) | 90 (22.3) | 80 (19.8) | ||
| 61–74 years | 429 (54.0) | 251 (61.0) | 234 (57.9) | 251 (62.1) | ||
| ≥ 75 years | 102 (12.9) | 80 (19.5) | 80 (19.8) | 73 (18.1) | ||
| Smoking history | 0.004 | 0.526 | ||||
| No | 510 (64.2) | 298 (72.5) | 299 (74.0) | 291 (72.0) | ||
| Yes | 284 (35.8) | 113 (27.5) | 105 (26.0) | 113 (28.0) | ||
| Drinking history | 0.775 | 0.836 | ||||
| No | 683 (86.0) | 356 (86.6) | 351 (86.9) | 349 (86.4) | ||
| Yes | 111 (14.0) | 55 (13.4) | 53 (13.1) | 55 (13.6) | ||
| Family history of tumor | 0.162 | 0.504 | ||||
| No | 577 (72.7) | 314 (76.4) | 315 (78.0) | 307 (76.0) | ||
| Yes | 217 (27.3) | 97 (23.6) | 89 (22.0) | 97 (24.0) | ||
| Recurrence during follow-up | 0.296 | 0.485 | ||||
| No | 722 (90.9) | 381 (92.7) | 379 (93.8) | 374 (92.6) | ||
| Yes | 72 (9.1) | 30 (7.3) | 25 (6.2) | 30 (7.4) | ||
| Lymph node metastasis | 0.096 | 0.806 | ||||
| No | 565 (71.2) | 311 (75.7) | 307 (76.0) | 304 (75.2) | ||
| Yes | 229 (28.8) | 100 (24.3) | 97 (24.0) | 100 (24.8) | ||
| Distant metastasis | 0.013 | 0.37 | ||||
| No | 673 (84.8) | 325 (79.1) | 332 (82.2) | 322 (79.7) | ||
| Yes | 121 (15.2) | 86 (20.9) | 72 (17.8) | 82 (20.3) | ||
| Tumor stage | 0.058 | 0.769 | ||||
| I | 338 (42.6) | 176 (42.8) | 185 (45.8) | 173 (42.8) | ||
| II | 200 (25.2) | 90 (21.9) | 91 (22.5) | 90 (22.3) | ||
| III | 135 (17.0) | 59 (14.4) | 56 (13.9) | 59 (14.6) | ||
| IV | 121 (15.2) | 86 (20.9) | 72 (17.8) | 82 (20.3) | ||
| Tumor differentiation | 0.267 | 0.606 | ||||
| Well differentiated | 379 (47.7) | 176 (42.8) | 189 (46.8) | 176 (43.6) | ||
| Moderately differentiated | 281 (35.4) | 158 (38.5) | 149 (36.9) | 154 (38.1) | ||
| Poorly differentiated | 134 (16.9) | 77 (18.7) | 66 (16.3) | 74 (18.3) | ||
| Treatment regimen | 0.008 | 0.723 | ||||
| Without chemo-radiotherapy | 492 (62.0) | 222 (54.0) | 227 (56.2) | 222 (55.0) | ||
| With chemo-radiotherapy | 302 (38.0) | 189 (46.0) | 177 (43.8) | 182 (45.0) |
Data are presented as n (%). CVMDs: cardiovascular and metabolic diseases.