Table 3.
Association between clinical features and ischemic heart disease in esophageal cancer patients
| Characteristics | Patients without ischemic heart disease (n = 1109) | Patients with ischemic heart disease (n = 96) | P value |
|---|---|---|---|
| Sex | 0.761 | ||
| Male | 676 (61.0) | 57 (59.4) | |
| Female | 433 (39.0) | 39 (40.6) | |
| Age | < 0.001 | ||
| ≤ 60 years | 334 (30.1) | 9 (9.4) | |
| 61–74 years | 626 (56.5) | 54 (56.2) | |
| ≥ 75 years | 149 (13.4) | 33 (34.4) | |
| Smoking history | 0.887 | ||
| No | 743 (67.0) | 65 (67.7) | |
| Yes | 366 (33.0) | 31 (32.3) | |
| Drinking history | 0.192 | ||
| No | 952 (85.8) | 87 (90.6) | |
| Yes | 157 (14.2) | 9 (9.4) | |
| Family history of tumor | 0.465 | ||
| No | 817 (73.7) | 74 (77.1) | |
| Yes | 292 (26.3) | 22 (22.9) | |
| Recurrence during follow-up | 0.667 | ||
| No | 1014 (91.4) | 89 (92.7) | |
| Yes | 95 (8.6) | 7 (7.3) | |
| Lymph node metastasis | 0.138 | ||
| No | 800 (72.1) | 76 (79.2) | |
| Yes | 309 (27.9) | 20 (20.8) | |
| Distant metastasis | 0.003 | ||
| No | 929 (83.8) | 69 (71.9) | |
| Yes | 180 (16.2) | 27 (28.1) | |
| Tumor stage | 0.004 | ||
| I | 473 (42.6) | 41 (42.7) | |
| II | 278 (25.1) | 12 (12.5) | |
| III | 178 (16.1) | 16 (16.7) | |
| IV | 180 (16.2) | 27 (28.1) | |
| Tumor differentiation | 0.214 | ||
| Well differentiated | 513 (46.2) | 42 (43.8) | |
| Moderately differentiated | 408 (36.8) | 31 (32.2) | |
| Poorly differentiated | 188 (17.0) | 23 (24.0) | |
| Treatment regimen | 0.001 | ||
| Without chemo-radiotherapy | 681 (61.4) | 33 (34.4) | |
| With chemo-radiotherapy | 428 (38.6) | 63 (65.6) |
Data are presented as n (%).