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. 2023 Sep 22;16:77–81. doi: 10.1016/j.sopen.2023.09.013

Table 2.

Continuous age-normalization for serum creatinine: the transformation for serum creatinine concentrations is presented here as a function of age and raw value, e.g., for a 15-month old patient with a serum creatinine level of 1.2, the value for the renal component of the CAN-SOFA score would be 3.33, as opposed to standard pediatric SOFA score of 3.

Creatinine:

Age Value Formula Value Formula Value Formula Value Formula Value Formula
<1 mo. <0.8 mg/dL 0 0.8–0.9 1 + (C-0.8) ∗ 10 1.0–1.1 2 + (C-1.0) ∗ 10 1.2–1.5 3 + (C-1.2) ∗ (10/3) >1.6 MIN(5,4 + C-1.6)
1–11 mo. <0.3 0 0.3–0.4 1 + (C-0.3) ∗ 10 0.5–0.7 2 + (C-0.5) ∗ 5 0.8–1.1 3 + (C-0.8) ∗ (10/3) >1.2 MIN(5,4 + C-1.2)
12–23 mo. <0.4 0 0.4–0.5 1 + (C-0.4) ∗ 10 0.6–1.0 2 + (C-0.6) ∗ 2.5 1.1–1.4 3 + (C-1.1) ∗ (10/3) >1.5 MIN(5,4 + C-1.5)
24–59 mo. <0.6 0 0.6–0.8 1 + (C-0.6) ∗ 5 0.9–1.5 2 + (C-0.9) ∗ (5/3) 1.6–2.2 3 + (C-1.6) ∗ (5/3) >2.3 MIN(5,4 + C-2.3)
60–143 mo. <0.7 0 0.7–1.0 1 + (C-0.7) ∗ (10/3) 1.1–1.7 2 + (C-1.1) ∗ 2 1.8–2.5 3 + (C-1.8) ∗ (10/7) >2.6 MIN(5,4 + C-2.6)
144–216 mo. <1.0 0 1.0–1.6 1 + (C-1) ∗ (5/3) 1.7–2.8 2 + (C-1.7) ∗ (10/11) 2.9–4.1 3 + (C-2.9) ∗ (5/6) >4.2 MIN(5,4 + C-4.5)
>18 yr. <1.2 0 1.2–1.9 1 + (C-1.2) ∗ (10/7) 2.0–3.4 2 + (C-2.0) ∗ (5/7) 3.5–4.9 3 + (C-3.5) ∗ (5/7) >5 MIN(5,4 + (C-5)/10)