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. 2023 Oct 9;2023(10):CD011769. doi: 10.1002/14651858.CD011769.pub2

Comparison 8. Atypical antipsychotic vs antiparkinsonian.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
8.1 Adverse effects: gastrointestinal 1   Risk Ratio (IV, Random, 95% CI) Subtotals only
8.1.1 Diarrhoea 1 18 Risk Ratio (IV, Random, 95% CI) 3.00 [0.14, 65.16]
8.1.2 Increased salivation 1 18 Risk Ratio (IV, Random, 95% CI) 3.00 [0.14, 65.16]
8.1.3 Vomiting 1 18 Risk Ratio (IV, Random, 95% CI) 0.20 [0.01, 3.66]
8.2 Adverse effects: metabolic 1   Risk Ratio (IV, Random, 95% CI) Subtotals only
8.2.1 Decreased appetite 1 18 Risk Ratio (IV, Random, 95% CI) 0.09 [0.01, 1.44]
8.3 Adverse effects: neurological 1   Risk Ratio (IV, Random, 95% CI) Subtotals only
8.3.1 Agitation/excitement 1 18 Risk Ratio (IV, Random, 95% CI) 1.50 [0.32, 6.94]
8.3.2 Increased hyperactivity 1 18 Risk Ratio (IV, Random, 95% CI) 7.00 [0.41, 118.69]
8.3.3 Insomnia 1 18 Risk Ratio (IV, Random, 95% CI) 2.00 [0.48, 8.31]
8.3.4 Sedation 1 18 Risk Ratio (IV, Random, 95% CI) 0.14 [0.01, 2.42]