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. 2023 Oct 9;2023(10):CD011769. doi: 10.1002/14651858.CD011769.pub2

Comparison 15. Typical antipsychotic vs placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
15.1 Self‐injury 1   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
15.2 Adverse effects: musculoskeletal 1   Risk Ratio (IV, Random, 95% CI) Subtotals only
15.2.1 Dystonia 1 23 Risk Ratio (IV, Random, 95% CI) 2.36 [0.11, 52.41]
15.3 Adverse effects: neurological 1   Risk Ratio (IV, Random, 95% CI) Subtotals only
15.3.2 Fatigue/lethargy 1 23 Risk Ratio (IV, Random, 95% CI) 8.64 [0.53, 140.05]
15.4 Adverse effects: psychological 1   Risk Ratio (IV, Random, 95% CI) Subtotals only
15.4.1 Behaviour problems 1 23 Risk Ratio (IV, Random, 95% CI) 0.34 [0.16, 0.73]
15.5 Tolerability/acceptabiity: loss to follow‐up 2 40 Risk Ratio (IV, Random, 95% CI) 0.46 [0.14, 1.49]