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. 2023 Oct 9;25:121. doi: 10.1186/s13058-023-01725-1

Table 1.

Characteristics of Premenopausal Women Recruited During Annual Screening Mammogram across Volumetric Percent Density Categoriesa

Almost entirely fatty < 3.5% (N = 35) Scattered areas of fibroglandular density 3.5% ~ 7.5% (N = 314) Heterogeneously dense > 7.5% ~ 15.5% (N = 197) Extremely dense > 15.5% (N = 154) Overall (N = 705)
Race
White 23 (65.7%) 203 (64.6%) 146 (74.1%) 130 (84.4%) 506 (71.8%)
Black 10 (28.6%) 94 (29.9%) 41 (20.8%) 17 (11.0%) 163 (23.1%)
Other 1 (2.9%) 15 (4.8%) 8 (4.1%) 7 (4.5%) 31 (4.4%)
Missing 1 (2.9%) 2 (0.6%) 2 (1.0%) 0 (0%) 5 (0.7%)
Age, years
Mean (SD) 46.2 (5.4) 46.3 (4.4) 46.0 (4.3) 45.2 (4.5) 46.0 (4.5)
Age at Menarche, years
Mean (SD) 12.5 (1.6) 12.4 (1.6) 12.8 (1.5) 13.0 (1.6) 12.7 (1.6)
Missing 1 (2.9%) 0 (0%) 1 (0.5%) 0 (0%) 2 (0.3%)
Body Shape at Age 10
1&2 8 (22.9%) 95 (30.3%) 96 (48.7%) 88 (57.1%) 290 (41.1%)
3&4 15 (42.9%) 111 (35.4%) 62 (31.5%) 49 (31.8%) 237 (33.6%)
5 6 (17.1%) 44 (14.0%) 24 (12.2%) 11 (7.1%) 85 (12.1%)
6–9 6 (17.1%) 39 (12.4%) 6 (3.0%) 1 (0.6%) 53 (7.5%)
Missing 0 (0%) 25 (8.0%) 9 (4.6%) 5 (3.2%) 40 (5.7%)
BMI, (kg/m2)
Mean (SD) 38.2 (6.8) 34.0 (6.9) 27.2 (4.9) 23.7 (3.7) 30.0 (7.5)
Body Fat, (%)
Mean (SD) 49.4 (5.1) 45.6 (6.9) 37.9 (7.3) 31.3 (7.4) 40.4 (9.3)
Missing 4 (11.4%) 14 (4.5%) 3 (1.5%) 4 (2.6%) 25 (3.5%)
Parity and Age at First Birth
Nulliparous 7 (20.0%) 67 (21.3%) 43 (21.8%) 43 (27.9%) 162 (23.0%)
1–2 children, < 25 years 6 (17.1%) 65 (20.7%) 24 (12.2%) 11 (7.1%) 107 (15.2%)
1–2 children,25–29 years 3 (8.6%) 44 (14.0%) 36 (18.3%) 27 (17.5%) 111 (15.7%)
1–2 children, ≥ 30 years 11 (31.4%) 53 (16.9%) 49 (24.9%) 43 (27.9%) 156 (22.1%)
 ≥ 3 children, < 25 years 3 (8.6%) 58 (18.5%) 15 (7.6%) 12 (7.8%) 88 (12.5%)
 ≥ 3 children, ≥ 25 years 5 (14.3%) 25 (8.0%) 30 (15.2%) 18 (11.7%) 79 (11.2%)
Missing 0 (0%) 2 (0.6%) 0 (0%) 0 (0%) 2 (0.3%)
Family History of Breast Cancer
No 29 (82.9%) 251 (79.9%) 152 (77.2%) 104 (67.5%) 540 (76.6%)
Yes 5 (14.3%) 57 (18.2%) 44 (22.3%) 46 (29.9%) 152 (21.6%)
Missing 1 (2.9%) 6 (1.9%) 1 (0.5%) 4 (2.6%) 13 (1.8%)
Oral Contraceptive Use, years
No 5 (14.3%) 42 (13.4%) 18 (9.1%) 16 (10.4%) 82 (11.6%)
 < 1 year 2 (5.7%) 27 (8.6%) 13 (6.6%) 12 (7.8%) 55 (7.8%)
1–4 years 9 (25.7%) 66 (21.0%) 31 (15.7%) 35 (22.7%) 141 (20.0%)
5–9 years 5 (14.3%) 59 (18.8%) 47 (23.9%) 30 (19.5%) 143 (20.3%)
 > 10 years 14 (40.0%) 119 (37.9%) 87 (44.2%) 60 (39.0%) 281 (39.9%)
Missing 0 (0%) 1 (0.3%) 1 (0.5%) 1 (0.6%) 3 (0.4%)
Alcohol consumption, /per week
0 drinks 13 (37.1%) 107 (34.1%) 51 (25.9%) 39 (25.3%) 211 (29.9%)
 < 1 drink 8 (22.9%) 85 (27.1%) 55 (27.9%) 32 (20.8%) 181 (25.7%)
1–2 drinks 9 (25.7%) 55 (17.5%) 37 (18.8%) 31 (20.1%) 133 (18.9%)
3–5 drinks 4 (11.4%) 46 (14.6%) 39 (19.8%) 37 (24.0%) 127 (18.0%)
6–10 drinks 0 (0%) 18 (5.7%) 12 (6.1%) 12 (7.8%) 43 (6.1%)
 > 10 drinks 1 (2.9%) 3 (1.0%) 3 (1.5%) 2 (1.3%) 9 (1.3%)
Missing 0 (0%) 0 (0%) 0 (0%) 1 (0.6%) 1 (0.1%)
VPD, (%)
Mean (SD) 3.15 (0.3) 5.16 (1.1) 10.9 (2.3) 22.6 (6.2) 10.5 (7.6)
DV, (cm3)
Mean (SD) 57.7 (20.6) 72.3 (33.5) 81.7 (41.4) 108 (62.2) 82.0 (45.5)
NDV, (cm3)
Mean (SD) 1870 (674) 1470 (690) 752 (392) 428 (258) 1060 (717)

a. 5 participants are missing VPD category, categories may not equal overall value

Abbreviations: standard deviation (SD), volumetric percent density (VPD), dense volume (DV), non-dense volume (NDV)