Table 5.
Nanocarrier Type | Drug Type | Release Mechanism | Release Rate | pH Sensitivity | Stability | References |
---|---|---|---|---|---|---|
Liposomes | Doxorubicin | pH Gradient | Sustained | Acidic | Stable | [13] |
Polymeric nanoparticles | Paclitaxel | Diffusion | Controlled | Neutral | Stable | [90, 102] |
Dendrimers | Methotrexate | Swelling | Pulsatile | Basic | Unstable | [99] |
Nanoemulsions | Docetaxel | Partitioning | Pulsatile | Acidic | Stable | [117] |
Gold nanoparticles | Curcumin | Photothermal | Triggered | Neutral | Stable | [90, 102] |
Iron oxide nanoparticles | Doxorubicin | Magnetic field | Sustained | Neutral | Stable | [121] |
Lipid-based | Paclitaxel | Diffusion | Sustained | Acidic | Stable | [57] |
Polymer-lipid hybrid | Cisplatin | Hydrolysis | Burst | Neutral | Unstable | [57] |
Carbon-based | Cisplatin | Adsorption | Triggered | Neutral | Unstable | [90, 102] |
Gold nanorods | Doxorubicin | Photothermal | Pulsatile | Neutral | Stable | [90, 102] |
Silica nanoparticles | Curcumin | pH-Responsive | Sustained | Neutral | Stable | [88] |
Polymer nanoparticles | Paclitaxel | Erosion | Sustained | Neutral | Stable | [90, 102] |
Liposomes | Curcumin | Gradient | Sustained | Neutral | Stable | [13] |
Gold nanoparticles | Doxorubicin | Photothermal | Pulsatile | Neutral | Stable | [90, 102] |
Polymeric micelles | Docetaxel | Solubilization | Controlled | Neutral | Stable | [91] |
Carbon nanotubes | Cisplatin | Diffusion | Sustained | Neutral | Unstable | [90, 102] |
Metal–organic frameworks | Methotrexate | Degradation | Sustained | Basic | Unstable | [101] |
Polymeric nanoparticles | Doxorubicin | Degradation | Sustained | Neutral | Stable | [90, 102] |
Liposomes | Methotrexate | pH Gradient | Controlled | Acidic | Stable | [13] |
Dendrimers | Paclitaxel | Swelling | Controlled | Neutral | Unstable | [99] |
Nanoemulsions | Curcumin | Partitioning | Sustained | Neutral | Stable | [117] |
Liposomes | Doxorubicin | pH Gradient | Sustained | Acidic | Stable | [13] |
Polymeric nanoparticles | Paclitaxel | Diffusion | Controlled | Neutral | Stable | [90, 102] |
Dendrimers | Methotrexate | Swelling | Pulsatile | Basic | Unstable | [99] |
Nanoemulsions | Docetaxel | Partitioning | Pulsatile | Acidic | Stable | [117] |
Gold nanoparticles | Curcumin | Photothermal | Triggered | Neutral | Stable | [117] |
Iron oxide nanoparticles | Doxorubicin | Magnetic field | Sustained | Neutral | Stable | [121] |
Lipid-based | Paclitaxel | Diffusion | Sustained | Acidic | Stable | [57] |
Polymer-lipid hybrid | Cisplatin | Hydrolysis | Burst | Neutral | Unstable | [57] |
Carbon-based | Cisplatin | Adsorption | Triggered | Neutral | Unstable | [90, 102] |
Gold nanorods | Doxorubicin | Photothermal | Pulsatile | Neutral | Stable | [58] |
Silica nanoparticles | Curcumin | pH-Responsive | Sustained | Neutral | Stable | [88] |