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. 2023 Oct 9;23:734. doi: 10.1186/s12903-023-03441-w

Table 1.

PICOS criteria for study inclusion

Parameter Inclusion criteria Exclusion criteria
Population Patients with a diagnosis of BMS according to the International Classification of Headache Disorders-3 (ICHD-3) [29]: patients presenting symptoms of oral burning or pain lasting more than 2 h per day for more than 3 months Any local or systemic factors that could produce the symptoms of oral burning pain, such as oral infections, oral lichen planus, or oral candidiasis
Intervention LLLT (600–1100 nm) was delivered directly to the site of pain; no limitations were placed on exposure duration or distance
Comparator No treatment or other treatments
Outcomes

Primary outcome:

1) Burning pain, measured using the Visual Analog Scale (VAS)

Secondary outcomes:

1) Oral health-related quality of life, assessed by the Oral Health Impact Profile-14 (OHIP-14);

2) Negative emotions, measured using the Hospital Anxiety and Depression Scale (HADS);

3) Other relevant outcomes and serious adverse events

Study design

1) Randomized controlled trials;

2) Published in English

1) Observational studies;

2) Non-randomized controlled trials;

3) Other types of studies