TABLE 1.
Treatment | No. of organisms recovered (103) on day:
|
|
---|---|---|
12 | 30 | |
Fluconazole | 4.5 ± 0.7 | NDb |
Cordycepin | 5.2 ± 0.2 | 210 ± 1 |
Coformycin | 4.1 ± 0.2 | 250 ± 70 |
Cordycepin + coformycin | 2.2 ± 0.3c | 4.3 ± 0.7d |
Prior to therapy there were 3.9 × 106 CFU/kidney (n = 2).
ND, not done because no mice survived to this point.
P = 0.021 versus value for treatment with cordycepin alone; P = 13 versus value for treatment with coformycin alone.
P = 0.005 versus value for treatment with either agent alone.