TABLE 2.
Treatment | No. of organisms recovered (103) on day:
|
|
---|---|---|
12 | 30 | |
Fluconazole | 5.8 ± 0.5 | NDb |
Cordycepin | 29 ± 8 | 240 ± 50 |
Coformycin | 33 ± 0.2 | 330 ± 20 |
Cordycepin + coformycin | 3.2 ± 0.3c | 4.9 ± 0.1d |
Prior to therapy there were 4.1 × 106 CFU/kidney (n = 2).
ND, not done because no mice survived to this point.
P ≤ 0.035 versus value for treatment with either agent alone.
P = 0.013 versus value for treatment with cordycepin alone; P = 0.002 versus value for treatment with coformycin alone.