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. 2023 Oct 6;11:e16164. doi: 10.7717/peerj.16164

Table 7. Enrichment analysis of top predicted phosphorylation substrates of HIPK3 kinase.

Category GO ID Term description Fold enrichment False discovery rate
Biological Process GO:0030518 Intracellular steroid hormone receptor signaling pathway 11.946 1.73E−02
GO:1903055 Positive regulation of extracellular matrix organization 11.946 8.43E−02
GO:1901522 Positive regulation of transcription from RNA polymerase II promoter involved in the cellular response to chemical stimulus 9.955 3.58E−02
GO:0040029 Regulation of gene expression, epigenetic 8.959 8.80E−07
GO:0035067 Negative regulation of histone acetylation 8.533 6.30E−02
GO:0001836 Release of cytochrome c from mitochondria 7.964 1.72E−03
Molecular Function GO:0051434 BH3 domain binding 12.008 2.03E−02
GO:0005496 Steroid binding 9.607 4.25E−02
GO:0097199 Cysteine-type endopeptidase activity involved in apoptotic signaling pathway 8.006 7.50E−02
GO:0070878 Primary miRNA binding 7.505 2.26E−02
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) 7.505 2.26E−02
Cellular Component GO:0035976 Transcription factor AP-1 complex 12.046 4.46E−02
GO:0071141 SMAD protein complex 9.637 8.63E−02
GO:0071159 NF-kappaB complex 9.637 8.63E−02
GO:0017053 Transcriptional repressor complex 5.815 5.34E−06
GO:0005667 Transcription factor complex 5.163 3.69E−17