Figure 4.

Frequency of peripheral blood monocyte subpopulations during the study period. Percentages of HLADR⁺CD33⁺CD14⁺CD16⁻ monocytes (A), HLADR⁺CD33⁺CD14⁻CD16⁺ monocytes (B), and HLADR⁺CD33⁺CD14⁺CD16⁺ monocytes (C) within CD45⁺ peripheral blood leukocytes in participants randomized to ORBCEL-M or placebo during the follow-up period. Values are expressed as median (IQR). *P < 0.05 between the ORBCEL-M and placebo groups (ANCOVA).