Skip to main content
. 2023 Oct 9;18(10):e0292591. doi: 10.1371/journal.pone.0292591

Table 4. Factor associated with overall survival.

Variables n/N (%) Cox regression analysis
HR 95% CI of HR P
Sex 0.196
Female (ref.) 2/33 (6) 1.00
Male 8/48 (17) 2.78 0.59–13.10
Age 0.979
> 51 (ref.) 5/40 (13) 1.00
≤ 51 5/41 (12) 1.02 0.29–3.52
Stage 0.906
Stage II (ref.) 2/21 (10) 1.00
Stage III 5/38 (13) 1.41 0.27–7.26
Stage IVA 3/22 (14) 1.44 0.24–8.63
NLR at pre-CCRT 0.940
Low (ref.) 5/40 (13) 1.00
High 5/41 (12) 0.95 0.28–2.30
ΔNLR at end-CCRT from pre-CCRT 0.506
Decrease (ref.) 1/15 (7) 1.00 -
Increase 9/66 (14) 2.02 0.26–15.91
ΔNLR at end-CCRT from pre-CCRT NA
Decrease (ref.) 0/21 (0) - -
Increase 10/60 (17) - -

Abbreviations: ref., reference group; HR, hazard ratio; aHR, adjusted hazard ratio; 95%CI, 95% confidence interval; NA, not applicable; NLR, neutrophil to lymphocyte ratio; CCRT, concurrent chemoradiotherapy; AC, adjuvant chemotherapy.