Table 1. Univariate analysis for 14- and 30-day mortality.
| Variables | 14-day mortality | p-value | OR | 95%CI | 30-day mortality | p-value | OR | 95%CI | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Present | Absent | Present | Absent | ||||||||
| Age | (years) | 53.45±4.17 | 64.10±2.51 | 0.029 * | 0.966 | 0.937–0.997 | 56.74±3.13 | 64.68±3.15 | 0.087 | – | – |
| Gender | Male Female |
12 10 |
21 19 |
0.877 | – | – | 19 15 |
14 14 |
0.644 | – | – |
| Hypertension | Present Absent |
6 16 |
26 14 |
0.006 * | 0.202 | 0.064–0.632 | 14 20 |
18 10 |
0.073 | – | – |
| Malignancy | Present Absent |
11 11 |
8 32 |
0.017 * | 4.000 | 1.280–12.502 | 12 22 |
7 21 |
0.383 | – | – |
| Immunosuppression | Present Absent |
13 9 |
7 33 |
0.001 * | 6.810 | 2.097–22.115 | 15 19 |
5 23 |
0.032 * | 3.632 | 1.115–11.824 |
| Bacteremia | Present Absent |
10 12 |
23 17 |
0.365 | – | – | 19 15 |
14 14 |
0.644 | – | – |
| CVVHF treatment | Present Absent |
10 12 |
11 29 |
0.157 | – | – | 17 17 |
4 24 |
0.005 * | 6.000 | 1.712–21.025 |
| APACHE-II score (at the diagnosis of infection) | (point) | 25.77±1.59 | 21.10±1.04 | 0.021 * | 1.105 | 1.015–1.203 | 24.53±1.20 | 20.61±1.31 | 0.040 * | 1.091 | 1.004–1.185 |
| SOFA score (at the diagnosis of infection) | (point) | 10.95±0.81 | 7.90±0.48 | 0.004 * | 1.303 | 1.091–1.558 | 10.68±0.61 | 6.93±0.48 | <0.001 * | 1.511 | 1.200–1.902 |
| Hypernatremia | Present Absent |
3 19 |
14 26 |
0.081 | – | – | 10 24 |
7 21 |
0.699 | – | – |
| Hypokalemia | Present Absent |
9 13 |
5 35 |
0.014 * | 4.846 | 1.368–17.171 | 10 24 |
4 24 |
0.164 | – | – |
| Daily fosfomycin dose (adjusted for creatinine clearance) | (g/day) | 12.86±0.82 | 11.86±0.74 | 0.399 | – | – | 12.08±0.69 | 12.37±0.92 | 0.802 | – | – |
*
p<0.05.