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. Author manuscript; available in PMC: 2023 Oct 9.
Published in final edited form as: Histopathology. 2023 May 18;83(3):406–413. doi: 10.1111/his.14959

Table 1:

HISTOLOGIC GRADING CRITERIA

GRADE Histologic criteria
1 Normal -sized nuclei or only mild nucleomegaly, no or only mild hyperchromasia, no mitoses, no nuclear stratification, no loss of cell polarity.
2 Moderate nucleomegaly and hyperchromasia, occasional mitoses, mild variation in nuclear size and contour, focal nuclear stratification and loss of polarity.
3 Marked nuclear enlargement, elongation and hyperchromaticiy, often with nuclear irregularity, frequent mitoses, diffuse concentric nuclear stratification and loss of polarity.