TABLE 2.

Structures and activities of various reexamined sulfanilamides  

Compoundf	Substituent at position:			IC50 (μM)
	R1	R2	R3

^aInhibition was tested at concentrations of 100 and 500 μM, and the resulting data were pooled with earlier inhibition data to generate IC₅₀s as reported previously (7). 

^bInhibition was tested at a concentration of 100 μM, and the resulting data were pooled with earlier inhibition data to generate IC₅₀s as reported previously (7). 

^cInhibition was tested at a concentration of 500 μM, and the resulting data were pooled with earlier inhibition data to generate IC₅₀s as reported previously (7). 

^dThe calculated IC₅₀ is outside of the experimental range. 

^e—, a negative correlation between the drug concentration and inhibition was noted. 

^fNumbers in boldface are compound numbers.