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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Nat Rev Genet. 2023 Jan 30;24(5):332–344. doi: 10.1038/s41576-022-00569-3

Figure 4. One example of how air pollution can trigger coordinated epigenetic and epitranscriptomic responses that impact human health.

Figure 4.

Exposure to particulate matter air pollution can trigger alterations in epitranscriptomic machinery and multiple other regulatory mechanisms that interact to generate a systemic response. In this example, air pollution exposure triggers changes in DNA methylation, small non-coding RNA, and epitranscriptomic machinery that may influence risk of pulmonary fibrosis.