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. 2023 Sep 21;55(10):1721–1734. doi: 10.1038/s41588-023-01504-w

Extended Data Fig. 7. Enrichments of R-loop kataegis across RTCA versus YTCA contexts.

Extended Data Fig. 7

a, b, Distributions of the fold-enrichment of RTCA versus YTCA sequence contexts within non-transcribed, transcribed, and intergenic regions (red, blue, and yellow lines, respectively). The Cohen’s D effect size was calculated for all pairwise region comparisons within R-loop kataegic events that include smaller clustered events (panel a) versus only larger kataegic events with ≥5 mutations per cluster (panel b). c, d, The same comparisons were performed for all kataegic events genome-wide that include smaller clustered events (panel c) and only larger kataegic events ≥5 mutations per cluster (panel d).