Table 3.
Regularized coefficients from the logistic regression with elastic net penalty
| Physical well-being (chest and upper body) | Sexual well-being | Psychosocial well-being | ||||
|---|---|---|---|---|---|---|
| Regularized coefficient for worsened physical well-being at 2 year follow-up | Regularized coefficient for improved physical well-being at 2 year follow-up | Regularized coefficient for worsened sexual well-being at 2 year follow-up | Regularized coefficient for improved sexual well-being at 2 year follow-up | Regularized coefficient for worsened psychosocial well-being at 2 year follow-up | Regularized coefficient for improved psychosocial well-being at 2 year follow-up | |
| Patient variables | ||||||
| Age | − 0.03 | − 0.06 | 0.15 | − 0.18 | 0.06 | |
| BMI | 0.01 | − 0.10 | − 0.01 | 0.09 | ||
| Diabetes | ||||||
| Yes | − 0.14 | − 0.38 | 0.23 | |||
| No | ||||||
| Smoker | ||||||
| Never | ||||||
| Previous | − 0.19 | − 0.05 | 0.24 | − 0.03 | ||
| Current | − 0.14 | − 0.12 | 0.07 | − 0.03 | ||
| Patient-reported outcomes at baseline | ||||||
| Satisfaction with breasts | 0.02 | 0.15 | − 0.23 | 0.10 | − 0.16 | |
| Psychosocial well-being | 0.04 | 0.03 | 0.02 | 0.77 | − 0.40 | |
| Physical well-being chest and upper body | 0.43 | − 1.08 | 0.02 | − 0.05 | − 0.01 | |
| Physical well-being abdomen | 0.17 | − 0.10 | ||||
| Sexual well-being | − 0.07 | 0.32 | − 0.78 | − 0.08 | − 0.08 | |
| Clinical variables | ||||||
| Radiation | ||||||
| After reconstruction | 0.40 | − 0.47 | 0.04 | − 0.44 | 0.24 | − 0.04 |
| Before reconstruction | 0.23 | − 0.20 | 0.14 | − 0.07 | 0.09 | |
| None | 0.17 | − 0.11 | ||||
| Mastectomy | ||||||
| Nipple sparing | − 0.02 | 0.14 | − 0.25 | |||
| Simple | ||||||
| Other | 0.65 | − 0.65 | ||||
| Reconstruction | ||||||
| Tissue expander (TE) | − 0.06 | 0.27 | − 0.51 | 0.43 | − 0.10 | |
| Direct-to-implant (DTI) | 0.07 | − 0.29 | 0.00 | |||
| Transverse rectus abdominis (TRAM) flap | 0.03 | − 0.06 | 0.09 | − 0.49 | 0.06 | |
| Deep inferior epigastric perforator (DIEP) flap | − 0.07 | 0.19 | − 0.11 | 0.23 | − 0.07 | 0.07 |
| Latissimus dorsi (LD) flap | 0.06 | 0.48 | − 0.63 | 0.24 | ||
| Gluteal artery perforator (GAP) flap | − 0.52 | − 0.80 | ||||
| Superficial inferior epigastric artery (SIEA) flap | − 0.15 | − 1.04 | 0.10 | |||
| Crossover flap | − 0.39 | − 0.17 | 0.42 | − 0.10 | ||
| Mixed flaps | − 0.24 | − 0.13 | 0.74 | − 0.06 | ||
| Mixed implants and autologous | 0.36 | − 0.88 | 0.12 | |||
| Chemotherapy | ||||||
| Received | 0.06 | 0.15 | − 0.21 | 0.26 | − 0.19 | |
| Not received | ||||||
| Laterality | ||||||
| Unilateral reconstruction | ||||||
| Bilateral reconstruction | − 0.01 | 0.07 | ||||
| Mastectomy indication | ||||||
| Therapeutic | ||||||
| Prophylactic | 0.17 | − 0.36 | ||||
| Axillary intervention | ||||||
| Axillary lymph node dissection (ALND) | 0.03 | − 0.17 | 0.14 | − 0.03 | − 0.03 | − 0.07 |
| Sentinel lymph node biopsy (SLNB) | 0.18 | 0.11 | ||||
| None | − 0.04 | − 0.11 | 0.05 | − 0.08 | 0.04 | |
Positive values indicate a positive correlation with the corresponding well-being, while negative values indicate a negative correlation with the corresponding well-being.