Table 2.

Adverse events during the treatment period

Type	Adverse event related to treatment	Grade 1	Grade 2	Grade 3
Constitutional	Fatigue	1 (8%)	1 (8%)
	Hypotension		1 (8%)
	Dizziness	1 (8%)
	Generalized muscle weakness	1 (8%)
	Muscle cramping	1 (8%)
	Noncardiac chest pain	1 (8%)
	Urine output decreased	1 (8%)
	Anorexia	2 (17%)
Gastrointestinal	Abdominal pain	3 (25%)	1 (8%)	1 (8%)
	Constipation	3 (25%)	1 (8%)
	Nausea/vomiting	3 (33%)	1 (8%)
	Ileus		1 (8%)
	Abdominal distention	2 (17%)
	Diarrhea	2 (17%)
Hematologic	Anemia	1 (8%)		1 (8%)
	Thrombocytopenia		1 (8%)
	Leukopenia	1 (8%)
Electrolyte abnormality	Hypophosphatemia		1 (8%)
	Hypernatremia	1 (8%)
	Hypoalbuminemia	1 (8%)
	Hypocalcemia	1 (8%)
	Hyponatremia	1 (8%)
	Hypokalemia	1 (8%)