Table 2.

Multivariable analysis with Cox proportional hazards for the prediction of cancer-specific survival of patients with non-muscle-invasive bladder cancer

Factors predicting cancer-specific survival—multivariable analysis
Variables		HR	95% CI	P-value
Tumor T category and grading	TaLG	ref		<.0001
	T1LG	2.532	2.163–2.963	<.0001
	TaHG	2.409	2.116–2.743	<.0001
	Tis	4.290	3.367–5.465	<.0001
	T1HG	5.382	4.847–5.976	<.0001
Age (years)	<60	ref		0.0001
	60-70	1.552	1.325–1.818	<.0001
	70-80	2.411	2.078–2.797	<.0001
	>80	5.252	4.541–6.074	<.0001
Tumor size	≥ 3 cm vs < 3 cm	1.308	1.206–1.419	<.0001
Tumor histology	Urothelial	ref		<.0001
	Squamous	1.315	1.112–1.554	<.0001
	Other	0.861	0.718–1.033	0.0001
Tumor location	Lateral/ posterior/ trigone	ref		<.0001
	Anterior/dome	1.087	0.926–1.276	0.3058
	Bladder neck	1.141	0.907–1.436	0.2611
	More than one area	1.445	1.281–1.630	<.0001
	Not specified/multiple	1.319	1.207–1.441	<.0001
History of previous NMIBC	Yes vs no	1.911	1.397–2.615	<.0001
Income	< $65,000 vs ≥ $65,000	1.186	1.097–1.281	<.0001
Marital status	Married*	ref		<.0001
	Unmarried	1.359	1.254–1.473	<.0001
	Status unkown	1.084	0.892–1.316	0.4166
Race	White	ref		0.0012
	Black	1.315	1.112–1.554	0.0013
	Other**	0.861	0.718–1.033	0.1064

*Partnership without official marriage was also regarded as married status.

**Includes American Indian/Alaska Native/Asian or Pacific Islander.