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. 2023 Sep 26;5:1203260. doi: 10.3389/fspor.2023.1203260

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© 2023 Funabashi, Tsuchida, Matsui, Kita and Nishijima.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Housing conditions used in the current study (A), and experimental design (B). A body-implantable actimeter to measure physical activity, nanotag®, was implanted intraperitoneally 1 week before measuring physical activity in mice of both groups. SH mice were housed in standard cages throughout the experiment, whereas EE mice were housed in standard, large, and extra-large cages for 5 days, followed by an extra-large cage with two floors and a variety of objects for 3 weeks. The period of physical activity measurement is indicated by a blank white arrow. At the end of the experiment, the brains of both the groups were removed.