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. 2023 Jan 19;78(10):1925–1932. doi: 10.1093/gerona/glad011

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Published by Oxford University Press on behalf of The Gerontological Society of America 2023.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 4. — Top predicted ASV log ratio is correlated with self-reported sleep quality index. The results of the linear regression model showing the top CoDaCoRe selected balance is significantly associated (beta = 0.38, 95% CI: 0.11–0.65; p < .05) with the self-reported Pittsburgh Sleep Quality Index, even after adjustment for all variables from the full model. The solid line and adjacent shaded area correspond to regression line and 95% CIs, respectively. The numerator consists of 4 ASVs classified as Ruthenibacterium lactatiformans, Bacteroides uniformis, Alistipes putredinis, and Escherichia dysenteriae; the denominator consists of 7 ASVs classified as Faecalibacterium prausnitzii_G, 2 ASVs of Prevotella copri_A, Bacteroides_B vulgatus, Buttiauxella agrestis, Ruminococcus_D bicirculans, and Oscillibacter valericigenes. ASV = amplicon sequence variant; CI = confidence interval.