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. 2023 May 29;78(10):1771–1777. doi: 10.1093/gerona/glad138

Figure 4.

Figure 4.

Association of proteins with Frailty Resilience Score. Volcano plot showing associated proteins as red dots (p value < 1.0 × 10−5). x-Axis denotes the beta estimate coefficient from linear model and y-axis shows the significance level presented as –log10 (p value). Top proteins have been annotated. ANTR2 = Anthrax toxin receptor 2; CD46 = Membrane cofactor protein; CSPG3 = Neurocan core protein; DNER = Delta and Notch-like epidermal growth factor-related receptor; ERBB1 = Epidermal growth factor receptor; FABP = Fatty acid-binding protein, heart; FABPA = Fatty acid-binding protein, adipocyte; FSTL3 = Follistatin-related protein 3; HHIP = Hedgehog-interacting protein; H6ST3 = Heparan-sulfate 6-O-sulfotransferase 3; HTRA1 = Serine protease HTRA1; IL-1Ra = Interleukin-1 receptor antagonist protein; MIC-1 = Growth/differentiation factor 15; PXDN = Peroxidasin homolog; SAP3 = Ganglioside GM2 activator; SRSF7 = Serine/arginine-rich splicing factor 7.