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. 2023 Sep 20;43(9):1509–1514. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2023.09.08

表 3.

分层交互分析不同亚组间胰岛素抵抗指数与血尿酸的关联

Hierarchical interaction analysis of the associations between insulin resistance index and Ua in different subgroups

Group Total Gender Age Glucose metabolism
Male Female ≥60 years <60 years T2DM Without T2DM
HOMA2-IR: HOMA2 insulin resistance; FCP: Fasting C-peptide; HOMA2 IR-CP: HOMA2 insulin resistance (C-peptide); T2DM: Type 2 diabetes.
HOMA2-IR Q1 1.0 1.0 1.0 1.0 1.0 1.0 1.0
Q2 1.36 (1.24-1.50) 1.37 (1.25-1.52) 1.02 (0.61-1.70) 1.10 (0.83-1.45) 1.39 (1.26-1.54) 1.38 (1.01-1.87) 1.32 (1.19-1.46)
Q3 1.61 (1.46-1.77) 1.60 (1.45-1.76) 2.07 (1.30-3.29) 1.19 (0.90-1.58) 1.66 (1.50-1.83) 1.47 (1.10-1.95) 1.56 (1.41-1.72)
Q4 1.90 (1.72-2.10) 1.85 (1.67-2.05) 3.48 (2.18-5.57) 1.43 (1.07-1.91) 1.95 (1.76-2.18) 1.78 (1.34-2.35) 1.84 (1.65-2.05)
P for trend <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
P for interaction - <0.001 <0.001 <0.001
HOMA2 IR-CP Q1 1.0 1.0 1.0 1.0 1.0 1.0 1.0
Q2 1.56 (1.40-1.74) 1.57 (1.40-1.76) 0.84 (0.49-1.45) 1.35 (0.95-1.92) 1.58 (1.40-1.77) 1.43 (0.90-2.29) 1.52 (1.36-1.71)
Q3 2.38 (2.14-2.65) 2.32 (2.08-2.59) 2.95 (1.86-4.68) 2.16 (1.54-3.02) 2.38 (2.13-2.66) 2.15 (1.39-3.33) 2.28 (2.04-2.55)
Q4 3.43 (3.06-3.84) 3.30 (2.94-3.72) 5.47 (3.38-8.84) 2.48 (1.75-3.54) 3.53 (3.13-3.98) 2.89 (1.88-4.44) 3.34 (2.96-3.77)
P for trend <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
P for interaction - <0.001 <0.001 <0.001