Table 2.
Univariate Cox analysis of risk factors for death within 28 days in patients
| Variables | Univariable COX | ||
|---|---|---|---|
| HR | 95% CI | P | |
| Age (years) | 0.998 | 0.9926,1.0035 | 0.483 |
| Gender (%) | |||
| Female | Ref. | ||
| Male | 1.0048 | 0.8528,1.1838 | 0.955 |
| Length of stay in hospital | 0.9962 | 0.9958,0.9967 | < 0.001 |
| Length of stay in ICU | 0.9986 | 0.9982,0.999 | < 0.001 |
| Vital signs | |||
| HR (beats/min) | 1.0036 | 1,1.0071 | 0.048 |
| SBP (mmHg) | 0.996 | 0.9927,0.9994 | 0.021 |
| DBP (mmHg) | 0.9949 | 0.9903,0.9995 | 0.029 |
| MAP (mmHg) | 0.994 | 0.9896,0.9984 | 0.008 |
| RR (t/min) | 1.02 | 1,1.03 | 0.015 |
| SpO2 (%) | 0.98 | 0.96,0.99 | 0.002 |
| Temperature (℃) | 0.93 | 0.86,1 | 0.064 |
| ALB (g/dL) | 0.79 | 0.7,0.9 | < 0.001 |
| Ferritin (ng/mL) (Log2) | 1.17 | 1.13,1.22 | < 0.001 |
| FAR (Log2) | 1.17 | 1.13,1.22 | < 0.001 |
| AG (mg/dL) | 1.04 | 1.02,1.05 | < 0.001 |
| Bicarbonate (mg/dL) | 0.98 | 0.96,0.99 | < 0.001 |
| Calcium (mg/dL) | 0.98 | 0.92,1.05 | 0.616 |
| Chloride, mean ± SD | 0.99 | 0.98,1 | 0.038 |
| Sodium (mEq/L) | 1.0003 | 0.9894,1.0113 | 0.959 |
| Potassium (mEq/L) | 1.03 | 0.96,1.12 | 0.396 |
| HCT (%) | 0.9954 | 0.984,1.007 | 0.438 |
| HGB (g/dL) | 0.99 | 0.95,1.02 | 0.471 |
| RBC (109/L) | 0.91 | 0.83,1 | 0.059 |
| RDW (%) | 1.04 | 1.01,1.07 | 0.004 |
| Glu (mg/dL) | 1 | 1,1 | < 0.001 |
| BUN (mg/dL) | 1.0032 | 1.0009,1.0055 | 0.006 |
| Crea (mg/dL) | 1.0008 | 0.9643,1.0387 | 0.968 |
| PLT (109/L) | 0.999 | 0.9984,0.9996 | 0.002 |
| WBC (109/L) | 1.0073 | 1.0024,1.0122 | 0.003 |
| Comorbidities, n(%) | |||
| Myocardial infarct | |||
| No | Ref. | ||
| Yes | 1.11 | 0.91,1.36 | 0.311 |
| Congestive heart failure | |||
| No | Ref. | ||
| Yes | 0.97 | 0.82,1.15 | 0.719 |
| Chronic pulmonary disease | |||
| No | Ref. | ||
| Yes | 1.13 | 0.95,1.34 | 0.169 |
| Diabetes | |||
| No | Ref. | ||
| Yes | 0.53 | 0.4,0.7 | < 0.001 |
| Renal disease | |||
| No | Ref. | ||
| Yes | 0.76 | 0.63,0.91 | 0.002 |
| Malignant cancer | |||
| No | Ref. | ||
| Yes | 0.91 | 0.74,1.13 | 0.39 |
| Severe liver disease | |||
| No | Ref. | ||
| Yes | 1.51 | 1.23,1.84 | < 0.001 |
| Metastatic solid tumor | |||
| No | Ref. | ||
| Yes | 1.6 | 1.25,2.03 | < 0.001 |
| Sofa score | 1.1 | 1.07,1.13 | < 0.001 |
HR heart rate, SBP systolic blood pressure, DBP diastolic blood pressure, MBP mean blood pressure, RR respiratory rate, SpO2 oxygen saturation, ALB albumin, FAR ferritin/albumin ratio, AG anion gap, HCT hematocrit, HGB hemoglobin, RBC red blood cells, RDW erythrocyte distribution width, Glu glucose, BUN blood urea nitrogen, Crea creatinine, PLT platelets, WBC white blood cell