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. 2023 Oct 10;28:414. doi: 10.1186/s40001-023-01405-y

Table 3.

Multivariate Cox regression analysis of risk factors for death within 28 days in patients

Variable Non-adjusted Model Model I Model II Model III
HR (95%CI) P value HR (95%CI) P value HR (95%CI) P value HR (95%CI) P value
Ferritin/albumin (Log2) 1.17 (1.13–1.22)  < 0.001 1.18 (1.13–1.23)  < 0.001 1.17 (1.11–1.24)  < 0.001 1.19(1.12–1.26)  < 0.001
Binary variable
Ferritin/Albumin < 364.2215 Ref. Ref. Ref. Ref.
Ferritin/albumin ≥ 364.2215 2.07 (1.75–2.44)  < 0.001 2.09 (1.77–2.47)  < 0.001 1.8 (1.49–2.17)  < 0.001 1.84(1.5–2.25)  < 0.001

Model I = Adjusted for age + gender. Model II = Model I + length of stay in hospital + length of stay in ICU + ALB + Ferritin + AG + Bicarbonate + Glu + Diabetes + Severe liver disease + Metastatic solid tumor + Sofa score. Model III = Model II + HR + SBP + DBP + MBP + RR + Spo2 + Temperature + Calcium + Chloride + Sodium + Potassium + HCT + HGB + RBC + RDW + BUN + Crea + PLT + WBC + Myocardial infarct + Congestive heart failure + Chronic pulmonary disease + Renal disease + Malignant cancer

HR heart rate, SBP systolic blood pressure, DBP diastolic blood pressure, MBP mean blood pressure, RR respiratory rate, SpO2 oxygen saturation, ALB albumin, FAR ferritin/albumin ratio, AG anion gap, HCT hematocrit, HGB hemoglobin, RBC red blood cells, RDW erythrocyte distribution width, Glu glucose, BUN blood urea nitrogen, Crea creatinine, PLT platelets, WBC white blood cell