Table 4.
Respondent-reported side effects (N=650)
| Currently taking | Previously taking | p-value Interference | |||
|---|---|---|---|---|---|
| N (%) reporting side effect | Interference* Median [IQR] | N (%) reporting side effect | Interference* Median [IQR] | ||
| Dry mouth | 194 (43.7%) | 0 [0, 1] | 54 (25.3%) | 1 [0, 3] | 0.015 |
| Drowsiness | 178 (40.1%) | 2 [0, 4] | 62 (29.1%) | 4 [1, 8] | 0.0004 |
| Increased Appetite | 135 (30.4%) | 0 [0, 1] | 36 (16.9%) | 3 [0, 5] | 0.0009 |
| Difficulty thinking straight | 80 (18.0%) | 4 [2, 6] | 46 (21.6%) | 7 [4.8, 9] | <0.0001 |
| Dizziness | 69 (15.5%) | 2 [1, 5] | 26 (12.2%) | 7 [3.8, 8.3] | <0.0001 |
| Fatigue | 58 (13.1%) | 3 [1, 6] | 22 (10.2%) | 7 [6, 9] | <0.0001 |
| Increased heart rate | 38 (8.6%) | 1 [0, 2] | 20 (9.4%) | 5 [2, 8] | <0.0001 |
| Headache | 25 (5.6%) | 2 [1, 4.5] | 9 (4.2%) | 5 [4, 7] | 0.063 |
| Irrational fears | 18 (4.1%) | 2.5 [1, 5.3] | 13 (6.1%) | 10 [6, 10] | 0.0005 |
| Nausea | 16 (3.6%) | 2 [0, 6] | 7 (3.2%) | 8 [3, 10] | 0.043 |
| None | 122 (27.5%) | 96 (45.1%) | |||
*
If a participant indicated that they experienced a side effect, they were asked to rate how much that side effect interfered with their daily activities.
The full sample for each group was used as the denominator for calculating percentages to represent the proportion of the total sample that endorsed each side effect.