Table 2.
Variable | All patients (n = 66) | Patients with hungry bone syndrome (n = 47) | Patients without hungry bone syndrome (n = 19) | P |
---|---|---|---|---|
Hemogram | ||||
White blood cell count, 103/µL | 7.6 ± 2.7 | 7.4 ± 2.8 | 8.1 ± 2.7 | 0.403 |
Red blood cell count, 106/µL | 3.3 ± 0.6 | 3.3 ± 0.6 | 3.3 ± 0.7 | 0.944 |
Hemoglobin, g/dL | 9.5 ± 1.7 | 9.5 ± 1.7 | 9.7 ± 1.8 | 0.689 |
Hematocrit, % | 28.8 ± 5.1 | 28.8 ± 5.0 | 28.9 ± 5.4 | 0.936 |
Mean corpuscular volume, fL | 87.4 ± 6.2 | 87.3 ± 6.5 | 87.6 ± 5.4 | 0.884 |
Platelet count, 103/µL | 290.6 ± 89.8 | 288.4 ± 91.3 | 296.0 ± 88.2 | 0.758 |
Biochemistry | ||||
Intact parathyroid hormone, pg/mL | 1768.4 ± 1480.3 | 1951.4 ± 1708.1 | 1315.9 ± 390.7 | 0.115 |
Aspartate aminotransferase, U/L | 20.4 ± 9.3 | 19.1 ± 8.6 | 23.5 ± 10.4 | 0.082 |
Alanine aminotransferase, U/L | 18.7 ± 21.1 | 19.0 ± 24.5 | 17.8 ± 7.7 | 0.829 |
Total bilirubin, mg/dL | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.3 ± 0.2 | 0.994 |
Fasting glucose, mg/dL | 113.0 ± 51.2 | 112.9 ± 58.2 | 113.5 ± 29.5 | 0.966 |
Uric acid, mg/dL | 7.1 ± 1.2 | 7.1 ± 1.2 | 7.1 ± 1.4 | 0.862 |
Blood urea nitrogen, mg/dL | 69.1 ± 18.3 | 70.5 ± 18.8 | 65.7 ± 16.8 | 0.338 |
Creatinine, mg/dL | 12.2 ± 2.6 | 12.2 ± 2.5 | 12.3 ± 2.9 | 0.822 |
Potassium, mEq/L | 3.9 ± 0.6 | 4.0 ± 0.6 | 3.6 ± 0.6 | 0.015a |
Sodium, mEq/L | 135.3 ± 3.7 | 135.2 ± 3.6 | 135.6 ± 4.2 | 0.726 |
Corrected calcium, mg/dL | 10.6 ± 0.9 | 10.4 ± 0.9 | 11.0 ± 0.8 | 0.014a |
Phosphate, mg/dL | 6.3 ± 1.3 | 6.4 ± 1.3 | 6.2 ± 1.5 | 0.687 |
Albumin, g/dL | 3.7 ± 0.4 | 3.7 ± 0.4 | 3.7 ± 0.4 | 0.731 |
Alkaline phosphatase, U/L | 159.7 ± 80.4 | 178.2 ± 87.5 | 115.0 ± 29.6 | 0.003b |
Total cholesterol, mg/dL | 197.4 ± 38.3 | 202.5 ± 39.5 | 184.8 ± 32.9 | 0.091 |
Triglycerides, mg/dL | 214.8 ± 167.4 | 201.4 ± 147.2 | 247.2 ± 209.5 | 0.320 |
Iron, µg/dL | 64.9 ± 25.4 | 64.7 ± 23.1 | 65.5 ± 31.2 | 0.912 |
Total iron binding capacity, µg/dL | 297.1 ± 60.1 | 287.8 ± 51.5 | 320.4 ± 74.2 | 0.051 |
Transferrin saturation, % | 22.1 ± 8.5 | 22.9 ± 8.7 | 20.3 ± 7.7 | 0.287 |
Ferritin, ng/mL | 301.6 ± 357.3 | 316.1 ± 367.5 | 268.0 ± 339.6 | 0.628 |
Dialysis-related data Dialysate calcium concentration |
0.979 | |||
2.5 mEq/L, n (%) | 45 (68.2) | 32 (68.1) | 13 (68.4) | |
3.5 mEq/L, n (%) | 21 (31.8) | 15 (31.9) | 6 (31.6) | |
PD modality | 0.133 | |||
CAPD, n (%) | 49 (74.2) | 32 (68.1) | 17 (89.5) | |
APD, n (%) | 7 (10.6) | 7 (14.9) | 0 (0) | |
CPAD/APD, n (%) | 10 (15.2) | 8 (17.0) | 2 (10.5) | |
Residual urine, mL/day | 136.0 ± 225.8 | 167.8 ± 257.3 | 57.4 ± 105.0 | 0.015a |
Kt/Vurea | 2.3 ± 0.3 | 2.3 ± 0.3 | 2.3 ± 0.3 | 0.962 |
Creatinine clearance, L/1.73 m2/week | 56.9 ± 8.9 | 55.8 ± 7.7 | 59.8 ± 11.4 | 0.106 |
Normalized protein catabolic rate, g/kg/day | 1.1 ± 0.2 | 1.1 ± 0.2 | 1.1 ± 0.3 | 0.896 |
Erythropoietin dose, unit/month | 18872.7 ± 4615.0 | 18410.3 ± 5432.4 | 20000.0 ± 0.0 | 0.250 |
aP < 0.05, bP < 0.01.
APD, automated peritoneal dialysis; CAPD, continuous ambulatory peritoneal dialysis; Kt/V urea, K dialyzer urea clearance; t, total dialysis session time; V, volume of distribution of urea.