Table 2. Diagnostic Parameters of ScreenDx-LungFibrosis™.
| Test parameter | Value | 95% confidence interval |
|---|---|---|
| Sensitivity (%) | 91.3 | 89.0 - 93.3 |
| Specificity (%) | 95.1 | 94.2 - 96.0 |
| LR+ | 18.8 | 15.8 - 22.9 |
| LR- | 0.09 | 0.07 - 0.11 |
| OR | 206.3 | 149.0 - 285.6 |
| PPV (%) | 84.8 | 82.1 - 87.3 |
| NPV (%) | 97.4 | 96.6 - 98.0 |
| PPV at low (10%) prevalence of PF (%) | 68.0 | 61.0 - 74.0 |
| NPV at low (10%) prevalence of PF (%) | 99.0 | 98.0 - 100.0 |
| PPV at high (50%) prevalence of PF (%) | 95.0 | 93.0 - 96.0 |
| NPV at high (50%) prevalence of PF (%) | 92.0 | 89.0 - 93.0 |
| Processing time (s), mean | 27.6 | 26.0 - 29.1 |
LR: likelihood ratio; OR: odds ratio; PPV: positive predictive value; NPV: negative predictive value.