Patterns of catamenial epilepsy. Day 1 is the first day of menstrual flow and day −14 is the day of ovulation. A, Normal cycle with normal ovulation. C1 pattern is associated with exacerbation of seizures in the perimenstrual phase (day −3 to day +3 of next cycle), and C2 pattern is associated with exacerbation of seizures in the periovulatory phase (day +10 to day −13). B, Inadequate luteal phase cycle with anovulation. The C3 pattern is associated with exacerbations during the entire inadequate luteal phase (day +10 to day +3 of the next cycle). C = catamenial seizure pattern; F = follicular phase; O = periovulatory phase; L = luteal phase; M = perimenstrual phase.Reprinted from Harden CL, Pennell PB, Lancet Neurol.1 © 2013, with permission from Elsevier. www.sciencedirect.com/science/article/pii/S1474442212702399.