Figure 4: Tissue-specific in vivo RNA targeting using a three-component CasRx system (reprinted5).
(A) Total inheritance percentage of triple transheterozygous flies carrying three transgenes (UASt-CasRx or UASt-dCasRx, gRNAs, and Gal4-driver. (B) Phenotypes of the triple transheterozygous flies. The white arrow indicates chitin pigment reduction in the thorax. Black and white fly marked with “X” represents lethality.