Table 4. Symptom reporting per participant during the study.

Reports of symptoms include physician documentation at clinic visits as well as parental reports via weekly phone calls. Resolution of symptoms was not recorded; the same episode of symptoms may have been reported more than once.

	Number of Reports of Symptoms Median (IQR)	Number of Reports of Symptoms Virus Positive Median (IQR)	Number of Reports of Symptoms Virus Negative Median (IQR)	Number of Reports of Symptoms with no Nasal Swabs obtained Median (IQR)
Any symptoms (Parental report + physician document)	11 (7, 15)	2 (0, 4)	3 (1, 5)	3 (0, 5)
Any nasal symptoms	7 (3, 10)	2 (0, 3)	2 (0, 3)	2 (0, 4)
Any cough	6 (3, 9)	1 (0, 3)	2 (0, 3)	2 (0, 4)
Wheeze	1 (0, 2)	0 (0, 1)	0 (0, 1)	0 (0, 1)
Altered breathing	0 (0, 2)	0 (0, 1)	0 (0, 0)	0 (0, 0)
Fever	0 (0, 1)	0 (0, 0)	0 (0, 0)	0 (0, 0)
Reduced activity	1 (0, 2)	0 (0, 1)	0 (0, 0)	0 (0, 0)
Nasal symptoms only (no cough, wheeze, or altered breathing)	4 (2, 6)	0 (0, 1)	1 (0, 2)	2 (0, 4)
Upper respiratory tract symptoms (cough, no wheeze or altered breathing)	5 (3, 7)	1 (0, 2)	2 (0, 4)	4 (2, 6)
Lower respiratory tract symptoms (wheezing and/or altered breathing)	1 (0, 4)	0 (0, 1)	0 (0, 1)	0 (0, 1)