TABLE 1. Characteristics of adults aged ≥60 years hospitalized with respiratory syncytial virus, COVID-19, or influenza — Investigating Respiratory Viruses in the Acutely Ill Network, 25 hospitals,* 20 U.S. states, February 1, 2022–May 31, 2023.
| Characteristic | No. (%) |
|||
|---|---|---|---|---|
| Total N = 5,784 | RSV n = 304 | COVID-19 n = 4,734 | Influenza n = 746 | |
|
Age, yrs, median (IQR)
|
74 (67–81)
|
72 (66–80) |
74 (67–82) |
71 (65–79) |
|
Age group, yrs
| ||||
| 60–69 |
2,038 (35.2)
|
116 (38.2) |
1,601 (33.8) |
321 (43.0) |
| 70–79 |
1,978 (34.2)
|
110 (36.2) |
1,623 (34.3) |
245 (32.8) |
| ≥80 |
1,768 (30.6)
|
78 (25.7) |
1,510 (31.9) |
180 (24.1) |
|
Race and ethnicity
| ||||
| Black or African American, non-Hispanic |
1,038 (17.9)
|
55 (18.1) |
795 (16.8) |
188 (25.2) |
| White, non-Hispanic |
3,659 (63.3)
|
178 (58.6) |
3,095 (65.4) |
386 (51.7) |
| Hispanic or Latino, any race |
702 (12.1)
|
44 (14.5) |
543 (11.5) |
115 (15.4) |
| Other race, non-Hispanic† |
293 (5.1)
|
22 (7.2) |
224 (4.7) |
47 (6.3) |
| Other§ |
92 (1.6)
|
5 (1.6) |
77 (1.6) |
10 (1.3) |
|
Sex
| ||||
| Female |
2,898 (50.1)
|
173 (56.9) |
2,326 (49.1) |
399 (53.5) |
| Male |
2,886 (49.9)
|
131 (43.1) |
2,408 (50.9) |
347 (46.5) |
|
HHS region*
| ||||
| 1 |
1,117 (19.3)
|
41 (13.5) |
971 (20.5) |
105 (14.1) |
| 2 |
337 (5.8)
|
27 (8.9) |
239 (5.0) |
71 (9.5) |
| 3 |
221 (3.8)
|
8 (2.6) |
199 (4.2) |
14 (1.9) |
| 4 |
998 (17.3)
|
59 (19.4) |
812 (17.2) |
127 (17.0) |
| 5 |
881 (15.2)
|
37 (12.2) |
712 (15.0) |
132 (17.7) |
| 6 |
676 (11.7)
|
25 (8.2) |
550 (11.6) |
101 (13.5) |
| 7 |
328 (5.7)
|
29 (9.5) |
246 (5.2) |
53 (7.1) |
| 8 |
731 (12.6)
|
51 (16.8) |
574 (12.1) |
106 (14.2) |
| 9 |
295 (5.1)
|
19 (6.3) |
257 (5.4) |
19 (2.6) |
| 10 |
200 (3.5)
|
8 (2.6) |
174 (3.7) |
18 (2.4) |
|
No. of organ systems with a chronic medical condition, median (IQR)¶
|
2 (2–3)
|
2 (2–3) |
2 (2–4) |
2 (2–3) |
|
COVID-19 vaccination status**
| ||||
| Unvaccinated |
997 (17.2)
|
29 (9.5) |
837 (17.7) |
131 (17.6) |
| Vaccinated†† |
4,713 (81.5)
|
274 (90.1) |
3,834 (81.0) |
605 (81.1) |
|
Influenza vaccination status§§
| ||||
| Unvaccinated |
2,548 (44.1)
|
131 (43.1) |
2,026 (42.8) |
391 (52.4) |
| Vaccinated¶¶ | 2,795 (48.3) | 147 (48.4) | 2,343 (49.5) | 305 (40.9) |
Abbreviations: HHS = U.S. Department of Health and Human Services; RSV = respiratory syncytial virus.
* Hospitals by HHS region include Region 1: Baystate Medical Center (Springfield, Massachusetts), Beth Israel Deaconess Medical Center (Boston, Massachusetts), and Yale University (New Haven, Connecticut); Region 2: Montefiore Medical Center (New York, New York); Region 3: Johns Hopkins Hospital (Baltimore, Maryland); Region 4: Emory University Medical Center (Atlanta, Georgia), University of Miami Medical Center (Miami, Florida), Vanderbilt University Medical Center (Nashville, Tennessee), and Wake Forest University Baptist Medical Center (Winston-Salem, North Carolina); Region 5: Cleveland Clinic (Cleveland, Ohio), Hennepin County Medical Center (Minneapolis, Minnesota), Henry Ford Health (Detroit, Michigan); The Ohio State University Wexner Medical Center (Columbus, Ohio), and University of Michigan Hospital (Ann Arbor, Michigan); Region 6: Baylor Scott & White Medical Center (Temple, Texas) and Baylor University Medical Center (Dallas, Texas); Region 7: Barnes-Jewish Hospital (St. Louis, Missouri) and University of Iowa Hospitals (Iowa City, Iowa); Region 8: Intermountain Medical Center (Murray, Utah) and UCHealth, University of Colorado Hospital (Aurora, Colorado); Region 9: University of Arizona Medical Center (Phoenix, Arizona), Stanford University Medical Center (Stanford, California), and UCLA Medical Center (Los Angeles, California); and Region 10: Oregon Health & Science University Hospital (Portland, Oregon) and University of Washington (Seattle, Washington).
† Other race, non-Hispanic includes American Indian or Alaska Native, Asian, and Native Hawaiian or other Pacific Islander, which were combined because of small counts.
§ Other includes patients who self-reported their race and ethnicity as “other” and those for whom race and ethnicity were unknown.
¶ Organ systems with chronic medical conditions include cardiovascular disease, neurologic disease, pulmonary disease, gastrointestinal disease, endocrine disease, kidney disease, hematologic disease, autoimmune disease, and immunocompromising conditions.
** A total of 74 (1.3%) patients were missing COVID-19 vaccination status, including one (0.3%) among RSV patients, 63 (1.3%) among COVID-19 patients, and 10 (1.3) among influenza patients.
†† Includes patients with receipt of ≥1 dose of original (ancestral) monovalent vaccines, specifically BNT1262b2, (Pfizer-BioNTech), mRNA-1273 (Moderna), NVX-CoV2373 (Novavax), Ad26.COV2.S (Janssen [Johnson & Johnson]) or patients with receipt of ≥1 dose bivalent (ancestral and BA.4/5) vaccines, specifically BNT1262b2 bivalent vaccine (Pfizer-BioNTech) and mRNA-1273.222 (Moderna) bivalent vaccine. Patients who received bivalent vaccination might have previously received 1–6 doses of the original (ancestral) monovalent vaccines.
§§ A total of 441 (7.6%) patients were missing influenza vaccination status, including 26 (8.6%) RSV patients, 365 (7.7%) COVID-19 patients, and 50 (6.7%) influenza patients.
¶¶ Patients were classified as vaccinated against influenza if they received season-specific influenza vaccination based on the period in which they were enrolled.