FIG. 4.

Inhibition of MSV-induced tumor development in SCID mice receiving a 10-day treatment with subcutaneous (s.c.) PMPA or oral bis(POC)-PMPA. The indicated doses are in milligrams of PMPA equivalent per kilogram per day. Data are the mean tumor sizes, measured on days 8, 10, and 13 postinfection. Drug-treated groups consisted of 10 mice; the untreated control group contained 20 mice.